Motor synergies: Evidence for a novel motor signature in autism spectrum disorder
| Autor: | S. Boni, Luciano Fadiga, C. Veronesi, G. Nazzaro, Maddalena Marini, Marco Emanuele, G. Polletta, Alessandro D'Ausilio |
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| Přispěvatelé: | Emanuele, M., Nazzaro, G., Marini, M., Veronesi, C., Boni, S., Polletta, G., D'Ausilio, A., Fadiga, L. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Linguistics and Language
Kinematics Autism Spectrum Disorder Cognitive Neuroscience Experimental and Cognitive Psychology Social behaviour Language and Linguistics NO Typically developing Motor synergies Neurodevelopmental disorder Machine learning Developmental and Educational Psychology medicine Motor synergie Humans Set (psychology) Child Social Behavior Autism spectrum disorder Early diagnosis Neurodevelopmental disorders Hand Strength Mechanism (biology) Communication Motor control Early diagnosi medicine.disease Kinematic Biomechanical Phenomena Coding system Psychology Cognitive psychology Human |
| Zdroj: | Cognition |
| Popis: | In autism spectrum disorder (ASD), socio-communicative impairments and stereotypical behaviours are paralleled by sensorimotor deficits. Individuals with ASD show an altered selection of motor parameters, resulting in clumsy and fragmented actions. Here, we investigated inter-joint coordination and motor synergies as a potential substrate of motor control problems in ASD. Synergies enable co-controlling redundant motor degrees of freedom (DoF, e.g. joint angles, muscles) by mapping behavioural goals into a flexible and low-dimensional set of variables. This mechanism simplifies motor control and helps to find unambiguous solutions for motor tasks. In a reaching-grasping paradigm, children with ASD showed reduced coupling between DoF, which correlated with socio-communicative symptoms severity. Impaired synergies may help to frame well-established motor problems in ASD, including impaired motor sequencing and abnormal trial-to-trial motor variability. On the other hand, synergies also provide an effective and compact coding system of observed actions. Impaired synergies may thus jeopardize motor interaction by initiating bottom-up cascade effects, leading to pervasive impairments of social behaviour. Finally, we trained an automatic classification algorithm to distinguish between ASD and typically developing (TD) participants based on reaching-grasping kinematics. Classification accuracy reached up to 0.947. This result corroborates and expands previous accounts claiming that motor-based early recognition is feasible and effective in ASD. |
| Databáze: | OpenAIRE |
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