Volumetric and visual assessment of the mesial temporal structures in Alzheimer's disease

Autor: Virginia Tuckwell, G. S. Robinson, Brian M. Tress, Patricia Desmond, J. G. Clement, David Ames, John T. O'Brien, Isaac Schweitzer, P. Clement
Rok vydání: 1994
Předmět:
Zdroj: Australian and New Zealand journal of medicine. 24(5)
ISSN: 0004-8291
Popis: Background: Alzheimer's disease is the commonest cause of dementia. Clinical diagnosis of Alzheimer's disease may be difficult. Magnetic resonance imaging has a role to play in diagnosis. Aim: To assess whether volumetric and/or visual assessment of the mesial temporal structures is useful in separating patients with Alzheimer's disease from age matched controls. Methods: Twenty-four patients with Alzheimer's disease diagnosed by NINCDS/ADRDA criteria and 15 age matched controls were studied with magnetic resonance imaging (MRI) and volumetric techniques. Segmented volumes of the mesial temporal structures were assessed visually and volumetrically. Results: Volumetric analysis demonstrated significant (p
Databáze: OpenAIRE