Volumetric and visual assessment of the mesial temporal structures in Alzheimer's disease
Autor: | Virginia Tuckwell, G. S. Robinson, Brian M. Tress, Patricia Desmond, J. G. Clement, David Ames, John T. O'Brien, Isaac Schweitzer, P. Clement |
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Rok vydání: | 1994 |
Předmět: |
Male
medicine.medical_specialty Pathology Temporal lobe Central nervous system disease Degenerative disease Discriminant function analysis Alzheimer Disease Internal Medicine Medical imaging medicine Dementia Humans Aged medicine.diagnostic_test business.industry Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging Temporal Lobe Female Radiology Alzheimer's disease business Tomography X-Ray Computed |
Zdroj: | Australian and New Zealand journal of medicine. 24(5) |
ISSN: | 0004-8291 |
Popis: | Background: Alzheimer's disease is the commonest cause of dementia. Clinical diagnosis of Alzheimer's disease may be difficult. Magnetic resonance imaging has a role to play in diagnosis. Aim: To assess whether volumetric and/or visual assessment of the mesial temporal structures is useful in separating patients with Alzheimer's disease from age matched controls. Methods: Twenty-four patients with Alzheimer's disease diagnosed by NINCDS/ADRDA criteria and 15 age matched controls were studied with magnetic resonance imaging (MRI) and volumetric techniques. Segmented volumes of the mesial temporal structures were assessed visually and volumetrically. Results: Volumetric analysis demonstrated significant (p |
Databáze: | OpenAIRE |
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