Medication Adherence in Patients Who Undergo Cardiac Transplantation
| Autor: | A. López Suárez, E. Lage Gallé, J.M. Sobrino Márquez, J. Rodríguez Rodríguez, A. Blanca Martínez Pérez |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Graft Rejection Male Health Knowledge Attitudes Practice medicine.medical_specialty Time Factors Medication adherence Disease Medication Adherence Therapeutic Adherence Risk Factors Internal medicine medicine Humans In patient Intensive care medicine Transplantation business.industry Graft Survival Mean age Middle Aged Cross-Sectional Studies Treatment Outcome Polypharmacy Heart Transplantation Drug Therapy Combination Female Surgery Transplant patient Observational study Drug Monitoring business Immunosuppressive Agents |
| Zdroj: | Transplantation Proceedings. 45:3662-3664 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2013.11.006 |
| Popis: | Background Heart transplant patients are required to take medication for life, both immunosuppressants to prevent rejection and any required for other illnesses. Treatment compliance can be measured quantitatively or qualitatively. Compliance measurement is not easy owing to different factors. The aim of this study was to assess the prevalence of therapeutic compliance in heart transplant patients. Methods We undertook a cross-sectional observational descriptive study. The sample comprised patients who received a heart transplant from 2001 to 2011. Of the 203 patients in total, we studied 99. We used the Morisky-Green test as an indirect method and recorded the immunosuppressant blood levels as a direct method. Results The mean age of the patients was 50 ± 12 years, and 84% were male. According to the Morisky-Green test, 33% of the patients were noncompliant, of whom 30% said they rarely forgot to take their medication. Patients took an average of 8 ± 3 drugs per day, but only 85% knew what the drugs were for; 24% of the patients had grade 3A rejection, and 65% had graft vessel disease. Conclusions Transplanted patients in this study showed a high level of therapeutic adherence that did not differ from other transplant series, either cardiac or other organs, nor from other chronic diseases. The results for defaulters were higher than that expected from these patients. The defaulter results were expected to be lower, given the information that the patients were supposed to have, both before and after the transplantation, and with the strict medical monitoring. Therefore, we have to stress therapeutic compliance, both medical and dietary-hygiene measures, and seek new strategies to improve the results. |
| Databáze: | OpenAIRE |
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