Clinical characteristics and mortality associated with COVID-19 in Jakarta, Indonesia: A hospital-based retrospective cohort study
| Autor: | Verry Adrian, Adhi Andrianto, Ngabila Salama, Raph L. Hamers, Lenny L Ekawati, J. Kevin Baird, Karina D Lestari, Iqbal R. F. Elyazar, Bimandra A Djaafara, Kartika Saraswati, Anuraj H Shankar, Rosa N Lina, Guy E. Thwaites, Henry Surendra, Widyastuti, Erlina Burhan, Dwi Oktavia |
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| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty Younger age Coronavirus disease 2019 (COVID-19) medicine.medical_treatment coronavirus Logistic regression children Internal Medicine medicine Intubation Mortality Proportional hazards model business.industry SARS-CoV-2 Health Policy Hazard ratio Public Health Environmental and Occupational Health Obstetrics and Gynecology COVID-19 Retrospective cohort study Odds ratio Hospital based medicine.disease Comorbidity Icu admission Psychiatry and Mental health Infectious Diseases Hospital outcomes Indonesia Pediatrics Perinatology and Child Health Geriatrics and Gerontology business Research Paper |
| Zdroj: | The Lancet Regional Health. Western Pacific |
| ISSN: | 2666-6065 |
| Popis: | BackgroundData on COVID-19-related mortality and associated factors from low-resource settings are scarce. This study examined clinical characteristics and factors associated with in-hospital mortality of COVID-19 patients in Jakarta, Indonesia, from March 2 to July 31, 2020.MethodsThis retrospective cohort included all hospitalised patients with PCR-confirmed COVID-19 in 55 hospitals. We extracted demographic and clinical data, including hospital outcomes (discharge or death). We used Cox regression to examine factors associated with mortality.FindingsOf 4265 patients with a definitive outcome by July 31, 3768 (88%) were discharged and 497 (12%) died. The median age was 46 years (IQR 32–57), 5% were children, and 31% had at least one comorbidity. Age-specific mortalities were 11% (7/61) for 3) symptoms; and shorter time from symptom onset to admission. Patients 1 comorbidity had a nearly six-fold higher risk of death than those without (adjusted hazard ratio 5·50, 95% CI 2·72-11·13; 27% vs 3% mortality).InterpretationOverall mortality was lower than reported in high-income countries, probably due to younger age distribution and fewer comorbidities. However, deaths occurred across all ages, with >10% mortality among children 50 years. |
| Databáze: | OpenAIRE |
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