Effect of matcha consumption on gut microbiota in healthy Japanese individuals: study protocol for a double-blind crossover interventional study
| Autor: | Takashi Yoshimura, Tomoki Miyoshi, Yuki Kitao, Masahide Hamaguchi, Naoko Nakanishi, Kazutsugu Kinoshita, Yoshitaka Hashimoto, Chihiro Munekawa, Tomonori Kimura, Hanako Nakajima, Michiaki Fukui, Takuro Okamura, Maya Takegami |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Journal of clinical biochemistry and nutrition. 70(3) |
| ISSN: | 0912-0009 0000-4030 |
| Popis: | Background: This study compares and clarifies the changes in intestinal flora resulting from the continuous consumption of two types of matcha.Methods: Healthy adults will consume two types of matcha tea for four weeks, and differences in the intestinal microflora before and after drinking will be compared. Gut microbiota will be identified using next-generation sequencing (NGS). Phylogenetic classification of the enterobacteria will be performed based on sequence similarities. The relative proportions of the classified enterobacteria to the total nucleotide sequences will be compared between the samples obtained from the two groups consuming different matcha.Discussion: The continuous consumption of matcha may improve dysbiosis and prevent atherosclerosis. The effects may vary according to the type of matcha used.Trial registration:The study was registered with university hospital medical information network (UMIN) (UMIN000040303), and all participants gave their written informed consent. Registered 1 November 2020, https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000045982. |
| Databáze: | OpenAIRE |
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