Association of Lower Serum Bilirubin With Loss of Residual Kidney Function in Peritoneal Dialysis Patients
| Autor: | Yasuhiro Kawai, Shigeru Tanaka, Kazuhiko Tsuruya, Toshiaki Nakano, Yuta Matsukuma, Takanari Kitazono, Hiroaki Tsujikawa, Masatoshi Hara, Kumiko Torisu |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Cirrhosis Bilirubin medicine.medical_treatment 030232 urology & nephrology Renal function 030204 cardiovascular system & hematology Chronic liver disease Kidney Function Tests Gastroenterology Peritoneal dialysis End stage renal disease Cohort Studies 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Humans Prospective Studies Renal Insufficiency Chronic Aged business.industry Hazard ratio Hematology Middle Aged medicine.disease chemistry Nephrology Disease Progression Female business Peritoneal Dialysis Kidney disease |
| Zdroj: | Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis TherapyREFERENCES. 24(2) |
| ISSN: | 1744-9987 |
| Popis: | Bilirubin is recognized as an endogenous antioxidant, and low serum bilirubin is reported to be associated with the progression of kidney disease. However, it is unclear whether serum bilirubin levels are associated with the loss of residual kidney function (RKF) in peritoneal dialysis (PD) patients. This study investigated the relationship between serum total bilirubin and loss of RKF. We prospectively followed 94 PD patients who started PD in our hospital between June 2006 and May 2016. Ten patients who had chronic liver disease or cirrhosis were excluded. Patients were divided into three groups based on serum total bilirubin concentration tertiles: tertile 1 (T1) < 0.3, T2 = 0.3, and T3 ≥ 0.4 mg/dL. We estimated the relationship between serum bilirubin and loss of RKF, defined as daily urine volume ( |
| Databáze: | OpenAIRE |
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