Multicomponent Reaction: Palladium-Catalyzed Carbonylation of Aryl Halides and Alkyl Halides to Aromatic Esters

Autor: Fengxiang Zhu, Pengpeng Yin, Pengbo Zhang
Rok vydání: 2022
Předmět:
Zdroj: The Journal of Organic Chemistry. 88:5153-5160
ISSN: 1520-6904
0022-3263
DOI: 10.1021/acs.joc.2c01794
Popis: A convenient four-component reaction has been developed that allows for the direct transformation of aryl iodides with alkyl halides into the corresponding aromatic esters and diesters via palladium-catalyzed carbonylation with water as solvent. Various esters and diesters were isolated in moderate to good yields with broad functional group tolerance.
Databáze: OpenAIRE