Impact of the Complexity of Bifurcation Lesions Treated With Drug-Eluting Stents
| Autor: | Nai-Liang Tian, Nigel Jepson, Shang-Yu Wen, Bo Xu, Chunguang Qiu, Tie-Ming Jiang, Michael S. Lee, Yan Wang, Teugh Sansoto, Imad Sheiban, Shao-Liang Chen, Haichang Wang, Qi Zhang, Tak W. Kwan, Feng Cao, Shuzheng Lv, Yaling Han, Liang-Long Chen, Fei Ye, Yao-Jun Zhang, Jun-Jie Zhang, Martin B. Leon, Chitprapai Paiboon |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Percutaneous coronary intervention Lesion Complexity Revascularization Drug-eluting stent Internal medicine Clinical endpoint medicine Cardiology cardiovascular diseases Stent thrombosis Radiology business Cardiology and Cardiovascular Medicine Bifurcation Mace |
| Zdroj: | JACC: Cardiovascular Interventions. 7(11):1266-1276 |
| ISSN: | 1936-8798 |
| DOI: | 10.1016/j.jcin.2014.04.026 |
| Popis: | Objectives The present study established criteria to differentiate simple from complex bifurcation lesions and compared 1-year outcomes stratified by lesion complexity after provisional stenting (PS) and 2-stent techniques using drug-eluting stents. Background Currently, no criterion can distinguish between simple and complex coronary bifurcation lesions. Comparisons of PS and 2-stent strategies stratified by lesion complexity have also not been reported previously. Methods Criteria of bifurcation complexity in 1,500 patients were externally tested in another 3,660 true bifurcation lesions after placement of drug-eluting stents. The primary endpoint was the occurrence of a major adverse cardiac event (MACE) at 12 months. The secondary endpoint was the rate of stent thrombosis (ST). Results Complex (n = 1,108) bifurcation lesions were associated with a higher 1-year rate of MACE (16.8%) compared with simple (n = 2,552) bifurcation lesions (8.9%) (p Conclusions Complex bifurcation lesions had higher rates of 1-year MACE and ST. The 2-stent and PS techniques were overall equivalent in 1-year MACE. However, 2-stent techniques for complex lesions elicited a lower rate of cardiac death and in-hospital MACE but higher rates of in-hospital ST and revascularization at 1 year for simple lesions. |
| Databáze: | OpenAIRE |
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