Adenylate kinase 2, a mitochondrial enzyme
| Autor: | V.M. Regina, Gail A. P. Bruns |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Adenylate kinase
Mitochondrion Mitogen-activated protein kinase kinase Hybrid Cells In Vitro Techniques Biochemistry Isozyme Phosphotransferase HeLa Mice Genetics Animals Humans Molecular Biology Ecology Evolution Behavior and Systematics Differential centrifugation biology Adenylate Kinase Phosphotransferases General Medicine biology.organism_classification AK2 Cell biology Mitochondria Isoenzymes HeLa Cells |
| Zdroj: | Biochemical genetics. 15(5-6) |
| ISSN: | 0006-2928 |
| Popis: | The subcellular compartmentalization of the isozymes of ATP: AMP phosphotransferase (adenylate kinase) was analyzed in HeLa cells, RAG cells, and RAG-human hybrids that express human AK-2. In HeLa cells and in the hybrids, human AK-2 was present in a mitochondrial fraction prepared from cell extracts and in mitochondria purified by density gradient centrifugation. Human AK-1 was, as expected, distributed in the soluble cytoplasmic fraction of the cells. The rodent isozymes which are homologous to human AK-1 and AK-2 have been determined. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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