Double-Clad Optical Fiber-Based Multi-Contrast Noncontact Photoacoustic and Fluorescence Imaging System
| Autor: | Jonghyun Eom, Jun Geun Shin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Fluorescence-lifetime imaging microscopy
Materials science Optical fiber Fluorophore TK7800-8360 Computer Networks and Communications Photoacoustic imaging in biomedicine multimodal imaging double-clad optical fiber coupler law.invention chemistry.chemical_compound noncontact photoacoustic imaging fluorescence imaging DCF lensed fiber Optics law Electrical and Electronic Engineering Multimodal imaging Inkwell business.industry Fluorescence Lens (optics) chemistry Hardware and Architecture Control and Systems Engineering Signal Processing Electronics business |
| Zdroj: | Electronics, Vol 10, Iss 3008, p 3008 (2021) Electronics; Volume 10; Issue 23; Pages: 3008 |
| ISSN: | 2079-9292 |
| Popis: | A noncontact photoacoustic and fluorescence dual-modality imaging system is proposed, which integrates a fiber-based fluorescence imaging system with noncontact photoacoustic imaging using a specially fabricated double-cladding fiber (DCF) coupler and a DCF lens. The performance of the DCF coupler and lens was evaluated, and the feasibility of this new imaging system was demonstrated using simple tubing phantoms with black ink and fluorophore. Our imaging results demonstrated that the multimodal imaging technique can simultaneously acquire photoacoustic and fluorescence images without coming into contact with the sample. Consequently, the developed method is the first noncontact scheme among multimodal imaging systems that is integrated with a photoacoustic imaging system, which can provide varied and complementary information about the sample. |
| Databáze: | OpenAIRE |
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