Autor:	Magdalena Murawska, Sigurd Braun
Rok vydání:	2022
Předmět:	Euchromatin Histones Heterochromatin Genetics Gene Silencing Chromatin
Zdroj:	Trends in Genetics. 38:646-649
ISSN:	0168-9525
DOI:	10.1016/j.tig.2022.02.011
Popis:	The multitasking histone chaperone FACT (FAcilitates Chromatin Transcription) contributes to actively transcribed euchromatin and repressed heterochromatin. However, its precise role in gene silencing has remained obscure. Here, we discuss new insights into the silent chromatin functions and recruitment mechanisms of FACT, and their possible implications in cell identity and cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cae4dc6367aa4b37076860767d059aa https://doi.org/10.1016/j.tig.2022.02.011 Zobrazit plný text záznamu Full Text from ScienceDirect