Lethal and atypical fetopathy caused by cytomegalovirus recurrence with isolated intra-abdominal complication in an immune woman
| Autor: | Maxime Pichon, Pascal Gaucherand, Y. Mekki, Alexandre Gaymard, Pierre-Adrien Bolze |
|---|---|
| Přispěvatelé: | Institut des Agents Infectieux [Lyon] (IAI), Hospices Civils de Lyon (HCL), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2018 |
| Předmět: |
Pathology
medicine.medical_specialty recurrence business.industry CMV Congenital cytomegalovirus infection echography medicine.disease [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM] [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology fetopathy Immune system [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology hyperechogenic bowel medicine [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie Complication business |
| Zdroj: | Medical Case reports and Reviews Medical Case reports and Reviews, 2018, 1, ⟨10.15761/mcrr.1000101⟩ |
| ISSN: | 2517-7214 |
| DOI: | 10.15761/mcrr.1000101 |
| Popis: | International audience; A pregnant woman did not show any problem during the first trimester, but ultrasound exam, confirmed by RMI, showed a large intra-abdominal hyper-echogenic cystic image at 24 weeks of gestation. Meconial peritonitis was suspected, complicated by stable splenomegaly. No neurological signs, variation of the amniotic fluid volume, cardiologic dysfunction or thrombocytemia was observed. Serological assays done before and during pregnancy showed constant low IgM and high IgG anti-CMV levels. Amniocentesis showed a high viral load in amniotic fluid. Fetal and maternal bleed were positive. The pregnancy was interrupted at 31 weeks without post-mortem fetal examination. Placenta revealed hydrophic villi with cytomegalic anti-CMV positive inclusions. This case of CMV recurrence leads to severe complications of the fetal development in a pregnant woman. The isolated abdominal abnormalities were an atypical presentation of fetal CMV, causing inappropriate decisions. Multiplex examinations on amniotic fluid would be keys during the pregnancy examination to prevent fatal outcomes. |
| Databáze: | OpenAIRE |
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