Perinatal depressive disorder prevalence in Africa: A systematic review and Bayesian analysis

Autor: Francky Teddy Endomba, Aude Laetitia Ndoadoumgue, Jean Joel Bigna, Celestin Danwang, Jan René Nkeck, Clarence M. Mbanga, Gregory Ayissi
Přispěvatelé: UCL - SSS/IREC/EPID - Pôle d'épidémiologie et biostatistique
Rok vydání: 2021
Předmět:
Zdroj: General hospital psychiatry, Vol. 69, p. 55-60 (2021)
ISSN: 0163-8343
DOI: 10.1016/j.genhosppsych.2021.01.006
Popis: Objective To curb the burden of perinatal depression (PND) in Africa, it is important to have an accurate estimate of its burden in the continent. Hence, we determined the prevalence of (major) depressive disorder in the perinatal period in Africa. Methods We searched PubMed, EMBASE, Africa Index Medicus, and Africa Journal Online, to identify studies reporting the prevalence of (major) depressive disorder in the perinatal period in Africa, between January 1st 2000 and February 17th 2020. PND prevalence was estimated using Bayesian modelling. Results We identified 154 studies (192 data points; 113,147 women). In pregnant women, the prevalence of depressive disorder was 22.8% (95%Credible interval [CrI]: 21.5–24.1) among women with no specific condition and 31.9% (95%CrI: 30.2–33.6) among those with HIV. In post-partum, the prevalence was 21.2% (95%CrI: 20.0–22.5), 30.0% (95%CrI: 28.2–31.8), and 44.6% (95%CrI: 35.9–53.8) among women with no specific condition, with HIV, and with poor pregnancy outcomes, respectively. Conclusions This study depicted a high prevalence of PND in Africa. This prevalence varied across pre-defined clinical profiles. HIV-infected women or those with poor pregnancy outcomes having a higher prevalence of depression. This highlights the need for more attention and preventive interventions geared towards these sub-groups.
Databáze: OpenAIRE