Epidemiological features of primary breast lymphoma patients and development of a nomogram to predict survival

Autor: Jingwen Li, Lisha Ai, Yu Hu, Fengjuan Fan, You Qin, Li Cai, Fei Peng, Shidai Mu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Oncology
Multivariate statistics
Lymphoma
PBL
primary breast lymphoma
MALT
mucosa-associated lymphoma
Nomogram
FL
follicular lymphoma
0302 clinical medicine
APC
annual percentage change
Epidemiology
030212 general & internal medicine
IPI
international prognostic index
RC254-282
Aged
80 and over
DSS
disease-specific survival
Incidence (epidemiology)
Incidence
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
General Medicine
Middle Aged
MCL
Mantle cell lymphoma
Prognosis
NHL
non-Hodgkin lymphoma
SBL
small B lymphocytic
Survival Rate
Primary breast lymphoma
030220 oncology & carcinogenesis
Original Article
Female
MZL
extranodal marginal zone lymphoma
DLBCL
diffuse large B-cell lymphoma
PH assumption
proportional hazards assumption
medicine.medical_specialty
TCL
T cell lymphoma
education
Breast Neoplasms
OS
overall survival
03 medical and health sciences
Primary Breast Lymphoma
Predictive Value of Tests
Internal medicine
SEER: database
Surveillance
Epidemiology
and End Results database
medicine
Overall survival
HL
Hodgkin lymphoma
Humans
ALCL
anaplastic large cell lymphoma
Aged
Neoplasm Staging
business.industry
Proportional hazards model
Patient survival
HRs
hazard ratios
LPL
lymphoplasmacytic lymphoma
CIs
confidence intervals
Survival Analysis
United States
SEER
Nomograms
BL
Burkitt lymphoma
Surgery
business
SEER Program
Zdroj: Breast, Vol 57, Iss, Pp 49-61 (2021)
The Breast : Official Journal of the European Society of Mastology
ISSN: 1532-3080
Popis: Background Studies on the epidemiology and prognosis of primary breast lymphoma (PBL) are lack for low incidence. Therefore, we aimed to investigate the epidemiological characteristics of PBL and develop nomograms to predict patient survival. Methods Data of patients who were diagnosed with PBL from 1975 to 2011 and incidence rate of PBL from 1975 to 2017 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Time-varying multivariable Cox regression analysis was performed to identify independent prognostic factors for overall survival (OS) and disease-specific survival (DSS). Nomograms were constructed based on the independent prognostic factors identified in multivariate Cox regression analysis. Results A total of 1427 patients diagnosed with PBL were identified with the average age of 67.1 years. The overall incidence of PBL is 1.35/1,000,000 (adjusted to the United States standard population in 2000) from 1975 to 2017, with a significant upward trend by an annual percentage change (APC) of 2.91 (95%CI 2.29–3.94, P
Highlights • The incident of PBL was calculated. • Nomograms were constructed to predict OS and DSS. • Patients are divided into the low-risk, medium-risk, and high-risk.
Databáze: OpenAIRE
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