Epidemiological features of primary breast lymphoma patients and development of a nomogram to predict survival
Autor: | Jingwen Li, Lisha Ai, Yu Hu, Fengjuan Fan, You Qin, Li Cai, Fei Peng, Shidai Mu |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Male
Oncology Multivariate statistics Lymphoma PBL primary breast lymphoma MALT mucosa-associated lymphoma Nomogram FL follicular lymphoma 0302 clinical medicine APC annual percentage change Epidemiology 030212 general & internal medicine IPI international prognostic index RC254-282 Aged 80 and over DSS disease-specific survival Incidence (epidemiology) Incidence Neoplasms. Tumors. Oncology. Including cancer and carcinogens General Medicine Middle Aged MCL Mantle cell lymphoma Prognosis NHL non-Hodgkin lymphoma SBL small B lymphocytic Survival Rate Primary breast lymphoma 030220 oncology & carcinogenesis Original Article Female MZL extranodal marginal zone lymphoma DLBCL diffuse large B-cell lymphoma PH assumption proportional hazards assumption medicine.medical_specialty TCL T cell lymphoma education Breast Neoplasms OS overall survival 03 medical and health sciences Primary Breast Lymphoma Predictive Value of Tests Internal medicine SEER: database Surveillance Epidemiology and End Results database medicine Overall survival HL Hodgkin lymphoma Humans ALCL anaplastic large cell lymphoma Aged Neoplasm Staging business.industry Proportional hazards model Patient survival HRs hazard ratios LPL lymphoplasmacytic lymphoma CIs confidence intervals Survival Analysis United States SEER Nomograms BL Burkitt lymphoma Surgery business SEER Program |
Zdroj: | Breast, Vol 57, Iss, Pp 49-61 (2021) The Breast : Official Journal of the European Society of Mastology |
ISSN: | 1532-3080 |
Popis: | Background Studies on the epidemiology and prognosis of primary breast lymphoma (PBL) are lack for low incidence. Therefore, we aimed to investigate the epidemiological characteristics of PBL and develop nomograms to predict patient survival. Methods Data of patients who were diagnosed with PBL from 1975 to 2011 and incidence rate of PBL from 1975 to 2017 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Time-varying multivariable Cox regression analysis was performed to identify independent prognostic factors for overall survival (OS) and disease-specific survival (DSS). Nomograms were constructed based on the independent prognostic factors identified in multivariate Cox regression analysis. Results A total of 1427 patients diagnosed with PBL were identified with the average age of 67.1 years. The overall incidence of PBL is 1.35/1,000,000 (adjusted to the United States standard population in 2000) from 1975 to 2017, with a significant upward trend by an annual percentage change (APC) of 2.91 (95%CI 2.29–3.94, P Highlights • The incident of PBL was calculated. • Nomograms were constructed to predict OS and DSS. • Patients are divided into the low-risk, medium-risk, and high-risk. |
Databáze: | OpenAIRE |
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