A glimpse of a putative pre-intron phase of eukaryotic evolution

Autor:	Alexander V. Sverdlov, Miklós Csürös, Eugene V. Koonin, Igor B. Rogozin
Rok vydání:	2006
Předmět:	Genetics animal structures Models Genetic fungi Group ii Intron Biology Introns Evolution Molecular Molecular evolution Evolutionary biology Gene Duplication Gene duplication Animals Humans Gene
Zdroj:	Trends in genetics : TIG. 23(3)
ISSN:	0168-9525
Popis:	Comparison of the exon–intron structures of ancient eukaryotic paralogs reveals the absence of conserved intron positions in these genes. This is in contrast to the conservation of intron positions in orthologous genes from even the most evolutionarily distant eukaryotes and in more recent paralogs. The lack of conserved intron positions in ancient paralogs probably reflects the origination of these genes during the earliest phase of eukaryotic evolution, which was characterized by concomitant invasion of genes by group II self-splicing elements (which were to become introns in the future) and extensive duplication of genes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9e6378f4e4e59d8179671f808657f3 https://pubmed.ncbi.nlm.nih.gov/17239982 Zobrazit plný text záznamu Full Text from ScienceDirect