Pathological characteristics of thyroid glands from Japanese Black Cattle living in the restricted area of the Fukushima Daiichi Nuclear Power Plant accident

Autor:	Hiroyuki Chida, Yoshitaka Deguchi, Masahiro Natsuhori, Kumiko Otani, Kenji Ochiai, Jun Sasaki, Takahisa Murata, Hiroshi Satoh, Itaru Sato, Megumi Uehara, Keiji Okada, Nobuhiko Ito
Rok vydání:	2019
Předmět:	Capsular Invasion endocrine system Pathology medicine.medical_specialty Goiter Neoplasms Radiation-Induced endocrine system diseases Thyroid Gland Cattle Diseases Biology Radiation Dosage 03 medical and health sciences Atrophy Japan Fibrosis medicine Animals Fukushima Nuclear Accident Humans Thyroid Neoplasms Pathological 030304 developmental biology 0303 health sciences Thyroid disease Thyroid 0402 animal and dairy science 04 agricultural and veterinary sciences General Medicine medicine.disease 040201 dairy & animal science Epithelium medicine.anatomical_structure Nuclear Power Plants Cattle General Agricultural and Biological Sciences
Zdroj:	Animal science journal = Nihon chikusan GakkaihoREFERENCES. 90(9)
ISSN:	1740-0929
Popis:	To study the effect of ionizing radiation on thyroid glands, 66 Japanese Black cattle residing in the restricted area of the Fukushima Daiichi Nuclear Power Plant in 2013-2017 were pathologically examined. There were no clinical symptoms of thyroid disease in these cattle. Three cases of goiter and seven of atrophy were found in two among the four farms examined. Cases of goiter exhibited normal morphological structure without mass or nodule formation in thyroid glands. Cellular atypia or capsular invasion of the follicular epithelium was absent. The estimated integrated dose of external radiation in goiter cases ranged from maximum 797 mSv to minimum 24 mSv. All lobules in the seven atrophic thyroid glands were affected, but pathological findings, such as inflammatory cell infiltration or stromal fibrosis, were not observed. The estimated integrated dose of external radiation in atrophic thyroids ranged from maximum 589 mSv to minimum 8 mSv. Immunohistochemical analysis of anti-nitroguanosine and the TUNEL method in goiter and atrophic thyroid glands did not reveal any positive findings. The present study indicates that there was no significant relationship between a radiation effect and pathological findings in any thyroid glands.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c974c9fdec3212d87ad856ce2683c3c https://pubmed.ncbi.nlm.nih.gov/31309667 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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