Diagnosis and Management of Squamous Cell Carcinoma of Unknown Primary in the Head and Neck: ASCO Guideline
| Autor: | Bruce H. Haughey, Rebecca D. Chernock, Umamaheswar Duvvuri, James Caudell, Matthew E. Witek, John Waldron, Ellie Maghami, Jessica L. Geiger, Cristina P. Rodriguez, Nofisat Ismaila, Hilda E. Stambuk, David J. Sher, Adriana Alvarez, Neil D. Gross, Doru Paul |
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| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
medicine.medical_specialty MEDLINE 03 medical and health sciences 0302 clinical medicine Health care Carcinoma Humans Medicine Basal cell 030223 otorhinolaryngology Head and neck Societies Medical Evidence-Based Medicine business.industry General surgery Evidence-based medicine Guideline Prognosis medicine.disease Oncology Head and Neck Neoplasms 030220 oncology & carcinogenesis Practice Guidelines as Topic Carcinoma Squamous Cell Unknown primary Neoplasms Unknown Primary business |
| Zdroj: | Journal of Clinical Oncology. 38:2570-2596 |
| ISSN: | 1527-7755 0732-183X |
| DOI: | 10.1200/jco.20.00275 |
| Popis: | PURPOSE To provide evidence-based recommendations to practicing physicians and other health care providers on the diagnosis and management of squamous cell carcinoma of unknown primary in the head and neck (SCCUP). METHODS The American Society of Clinical Oncology convened an Expert Panel of medical oncology, surgery, radiation oncology, radiology, pathology, and advocacy experts to conduct a literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and prospective and retrospective comparative observational studies published from 2008 through 2019. Outcomes of interest included survival, local and regional disease control, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. RESULTS The literature search identified 100 relevant studies to inform the evidence base for this guideline. Four main clinical questions were addressed, which included subquestions on preoperative evaluations, surgical diagnostic and therapeutic procedures, appropriate pathology techniques, and adjuvant therapy. RECOMMENDATIONS Evidence-based recommendations were developed to address preoperative evaluation for patients with a neck mass, surgical diagnostic and therapeutic procedures, appropriate treatment options in unilateral versus bilateral SCCUP. Additional information is available at www.asco.org/head-neck-cancer-guidelines . |
| Databáze: | OpenAIRE |
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