Data from Use of the Predictive Sugars Biomarker to Evaluate Self-Reported Total Sugars Intake in the Observing Protein and Energy Nutrition (OPEN) Study

Autor: Victor Kipnis, Arthur Schatzkin, Sheila A. Bingham, Amanda J. Cross, Amy F. Subar, Nancy Potischman, Douglas Midthune, Nataša Tasevska
Rok vydání: 2023
DOI: 10.1158/1055-9965.c.6514786.v1
Popis: Background: A predictive biomarker for intake of total sugars was recently developed under controlled conditions. We used this biomarker to assess measurement error (ME) structure in self-reported intake of total sugars in free-living individuals.Methods: The Observing Protein and Energy Nutrition (OPEN) study involved 484 participants aged 40 to 69 years. Diet was assessed using two administrations of a food frequency questionnaire (FFQ) and two nonconsecutive 24-hour dietary recalls (24HDR). Two 24-hour urine samples checked for completeness were analyzed on sucrose and fructose. We applied the biomarker calibrated in a feeding study to OPEN data to assess the ME structure and the attenuation factors (AF) for intakes of absolute total sugars and sugars density for the FFQ and 24HDR.Results: The AFs for absolute sugars were similar for a single FFQ and 24HDR, but attenuation decreased with repeated 24HDRs. For sugars density, the AFs for FFQ (men: 0.39; women: 0.33) were greater than for single 24HDR (men: 0.30; women: 0.24), and similar to two 24HDRs (men: 0.41; women: 0.35). The attenuation associated with both instruments was greater in women than in men.Conclusions: Both the FFQ and 24HDR were found to be biased; hence, incorporation of the sugars biomarker in calibration studies within the cohorts may be necessary to more reliably estimate associations of sugars and disease.Impact: In this article, we propose a new dietary reference instrument based on the recently defined class of predictive biomarkers. Using sugars biomarker, we quantify ME in the FFQ- and 24HDR-reported absolute total sugars and total sugars density. Cancer Epidemiol Biomarkers Prev; 20(3); 490–500. ©2011 AACR.
Databáze: OpenAIRE