Topical steroid-antibiotic combinations: assay of use in experimentally induced human infections
| Autor: | Albert M. Kligman, Richard R. Marples, Alfredo Rebora |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Adult
Nystatin Triamcinolone acetonide medicine.drug_class Administration Topical medicine.medical_treatment Antibiotics Anti-Inflammatory Agents Dermatology Candidiasis Cutaneous medicine.disease_cause Staphylococcal infections Triamcinolone Acetonide Microbiology Candida albicans medicine Humans Skin Diseases Infectious Glucocorticoids biology business.industry Tyrothricin Neomycin General Medicine Staphylococcal Infections biology.organism_classification medicine.disease Anti-Bacterial Agents Drug Combinations Evaluation Studies as Topic Staphylococcus aureus business Topical steroid medicine.drug |
| Zdroj: | Archives of Dermatology. 108:237-240 |
| ISSN: | 0003-987X |
| DOI: | 10.1001/archderm.108.2.237 |
| Popis: | Whether antibiotics should be combined with topical steroids in the treatment of chronic dermatoses is a question that is extraordinarily difficult to answer. The alternative proposed in this study is appraisal of efficacy in experimental human infection with Staphylococcus aureus and Candida albicans . With a broad spectrum steroid-antibiotic combination containing triamcinolone acetonide, neomycin gramicidin, and nystatin, it was possible to show that omission of any one component decreased the effectiveness of the mixture. The steroid by itself suppressed the experimental lesion without influencing the multiplication of the pathogen. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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