Combined Embolization and Gamma Knife Radiosurgery for Cerebral Arteriovenous Malformations
| Autor: | P. Svendsen, C. Lindquist, Bengt Karlsson, Kaj Ericson, Wan-Yuo Guo, G. Wikholm |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
medicine.medical_specialty
Radiological and Ultrasound Technology medicine.diagnostic_test business.industry medicine.medical_treatment Gamma knife radiosurgery Arteriovenous malformation General Medicine medicine.disease Radiosurgery 030218 nuclear medicine & medical imaging Cerebral arteriovenous malformations Radiation therapy 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Medicine Local irradiation Radiology Nuclear Medicine and imaging Embolization Radiology business Cerebral angiography |
| Zdroj: | ResearcherID |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1177/028418519303400614 |
| Popis: | In a study of 46 patients with cerebral arteriovenous malformations (AVMs) the value of combining embolization and gamma knife radiosurgery was assessed. In 35 patients with large grade III to V AVMs (Spetzler-Martin system) staged combined treatment was planned. In 11 patients, radiosurgery complemented embolization for a residual AVM. The number of embolization sessions ranged from 1 to 7 (median 2). Twenty-six patients needed multiple embolization sessions. In 28 patients the grade of AVMs decreased as a result of embolization. In 16 patients collateral feeding vessels developed after embolization which made delineation of the residual nidus difficult. The time lag between the last embolization and radiosurgery ranged from 1 to 24 months (median 4). Nineteen of 35 large grade III to V AVMs were possible to treat by radiosurgery following embolization. In the 46 patients complications occurred in 9 from embolization and in 2 from radiosurgery. Two patients had transient and 9 had permanent neurologic deficits. It is concluded that embolization facilitates radiosurgery for some large AVMs and therefore this combined treatment has a role in the management of AVMs. |
| Databáze: | OpenAIRE |
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