The effect of ace inhibition on peripheral hemodynamics in normotensive and hypertensive patients with type II diabetes
| Autor: | Pier Luigi Malini, Adolfo Ciavarella, Giampaolo Valtancoli, Ettore Ambrosioni, Anna Mustacchio, P. Vannini, Cristina Ricci, Enrico Strocchi |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Hemodynamics Angiotensin-Converting Enzyme Inhibitors Essential hypertension Forearm Enalapril Internal medicine medicine Humans Pharmacology (medical) Pharmacology Chemotherapy biology business.industry Angiotensin-converting enzyme Middle Aged medicine.disease Endocrinology medicine.anatomical_structure Diabetes Mellitus Type 2 Enzyme inhibitor ACE inhibitor Hypertension Cardiology biology.protein Female Vascular Resistance business Diabetic Angiopathies medicine.drug |
| Zdroj: | Journal of clinical pharmacology. 31(2) |
| ISSN: | 0091-2700 |
| Popis: | The effect of treatment with enalapril (10 days at 10 mg/d followed by 4 weeks at 20 mg/d) on forearm hemodynamics was assessed in eight normotensive patients and eight patients with hypertension affected by Type II diabetes as well as in eight patients with essential hypertension and normal glucose tolerance. The ACE inhibitor decreased regional vascular resistances and increased the maximum arteriolar-vasodilating capacity and venous distensibility in the three groups of patients. Thus, this study shows that ACE inhibition by enalapril improves regional hemodynamics in patients with Type II diabetes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text