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The long-term goal of our laboratory is to underst and vertebrate host recognition of microbial pathogens. Although, our work is primarily curiosity driven, it is certainly true that understanding how a host recognizes microbial pathogens should have some medical application. Probably more than 50,000 people die each year in the United States of septic shock or the systemic inflammatory response syndrome, and there is no good therapy for this problem. Understanding the molecular basis of itsorigin should suggest novel therapeutic approaches. |
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