Pigmented Lesions of the Nail Unit
Autor: | Marely Santiago-Vazquez, Oscar W Nevares-Pomales, Julián Barrera-Llaurador, Jorge L. Sánchez, Carlos J. Sarriera-Lázaro, Nahyr Lugo-Fagundo, Julio E Sanchez |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
business.industry Dermatology General Medicine Pathology and Forensic Medicine Nail Diseases 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Nail (anatomy) Humans Medicine Differential diagnosis business Pigmentation Disorders |
Zdroj: | The American Journal of Dermatopathology. 40:793-804 |
ISSN: | 0193-1091 |
Popis: | Pigmented lesions of the nail unit are commonly encountered in the clinical setting. Yet, they often present a unique challenge to clinicians because of a broad differential diagnosis or unfamiliarity with clinical and histopathologic features. A wide variety of causes exist ranging from benign lesions such as subungual hemorrhage to malignant lesions such as subungual melanoma. Identifying the underlying cause is key to appropriate management and follow-up in these patients. Although emerging clinical tools such as dermoscopy can be very useful in evaluation of these lesions, histopathologic analysis remains the gold standard. In this review, we discuss and provide a summary of important clinical and histopathological concepts of pigmented lesions of the nail unit with special focus on longitudinal melanonychia, melanotic macule, melanocytic nevus, subungual melanoma, along with discussion of some nonmelanocytic lesions. |
Databáze: | OpenAIRE |
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