Midterm outcome of ultrasound-guided alcohol gel sclerotherapy for symptomatic leiomyoma
| Autor: | Valeria Maria Bezerra Silva, Fernando Viana Gurgel, Mirela Ávila, Maria da Conceição Souto Maior, Lucilo Avila Pessoa |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Uterus Surveys and Questionnaires Sclerotherapy Medicine Humans Radiology Nuclear Medicine and imaging Adverse effect Ultrasonography Interventional Uterine leiomyoma Chi-Square Distribution Radiological and Ultrasound Technology Ethanol Leiomyoma business.industry Pelvic pain Ultrasound Middle Aged medicine.disease Surgery medicine.anatomical_structure Treatment Outcome Uterine Neoplasms Female medicine.symptom business Chi-squared distribution Gels |
| Zdroj: | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 29(9) |
| ISSN: | 1550-9613 |
| Popis: | Objective The purpose of this study was to describe the outcome of ultrasound-guided ethanol gel sclerotherapy of myomatous nodules 1 to 18 months after treatment. Methods A total of 118 consecutive patients with a diagnosis of symptomatic leiomyomas referred for ethanol gel sclerotherapy were studied between November 2005 and July 2007. Clinical (self-administered symptom questionnaire) and ultrasound follow-ups were done 1 to 2, 6 to 8, and 12 to 18 months after the procedure. Results The mean baseline volumes +/- SD were 223.3 +/- 158.3 cm(3) for the uterus and 68.4 +/- 110.5 cm(3) for the dominant fibroid. The most common adverse reaction in the immediate postoperative period was pelvic pain in 27.1% of the patients, but 58.4% had no reactions. After 12 months, a 29.5% reduction in uterine volume was observed in 64.7% of the patients. A 55.5% reduction in dominant fibroid volume was observed in 82.8% of the patients. Pelvic pain improved in 29.8% of the sample, dysmenorrhea in 51.7%, and menstrual flow in 39%. Most patients (77%) reported being satisfied or very satisfied with the treatment. Conclusions The results suggest that ethanol gel sclerotherapy is a safe, conservative alternative for treating symptomatic uterine leiomyomas. Further randomized studies are necessary to determine the suitability and indications of this procedure in comparison to other minimally invasive techniques. |
| Databáze: | OpenAIRE |
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