Introduction of new Tumor Marker Age Score in clinical practice: Validity evaluation for differentiation benign from malignant adnexal masses
| Autor: | Jelena Dotlic, Branka Nikolic, Ivana Likić Ladjević, Milan Terzic, Svetlana J Milenkovic, S. Maricic, Nebojsa Ladjevic, Nebojsa Arsenovic, Jovan Bila, I Pilic, Natasa Brndusic, Nebojsa Nick Knezevic |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Ovarian Neoplasms medicine.medical_specialty Pathology business.industry Ovary General Medicine Middle Aged Gastroenterology Sensitivity and Specificity Adnexal tumors Clinical Practice Diagnosis Differential medicine.anatomical_structure Internal medicine Adnexal Diseases medicine Biomarkers Tumor Humans Tumor type In patient Female Ovarian Diseases business Tumor marker |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0354-950X |
| Popis: | OBJECTIVE: The aim of the study was to examine several tumor markers and their correlation with pathohistological findings in patients with adnexal masses. METHODS: Study involved 139 patients, 84 of them with benign, 47 with malignant and 8 with borderline adnexal tumor. Levels of CA 125, CA 19-9, CEA and CA 15-3 were obtained preoperatively and assessed regarding the specific pathohistological diagnose and the patient’s age. Obtaining these results led us to divide the patient’s CA 125 levels with age and by doing that we have attained a new Tumor Marker Age score (TMA score). Results: Patients with malignant adnexal tumors had significantly higher levels of CEA (p |
| Databáze: | OpenAIRE |
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