Cartilage Micrografts as a Novel Non-Invasive and Non-Arthroscopic Autograft Procedure for Knee Chondropathy: Three-Year Follow-Up Study
| Autor: | Marcello Zappia, Antonio Graziano, Marco Marcarelli, Letizia Trovato, Carlo Astarita, Lorenzo Rissolio, Chiara Baroni |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Chondropathy
medicine.medical_specialty Visual analogue scale regenerative medicine lcsh:Medicine Article Cartilage micrografts Medical device Regenerative medicine 03 medical and health sciences 0302 clinical medicine Analgesic therapy medicine 030212 general & internal medicine medicine.diagnostic_test business.industry medical device Cartilage Non invasive lcsh:R Follow up studies Magnetic resonance imaging General Medicine medicine.disease Surgery medicine.anatomical_structure 030220 oncology & carcinogenesis business cartilage micrografts Oxford knee score |
| Zdroj: | Journal of Clinical Medicine, Vol 10, Iss 322, p 322 (2021) Journal of Clinical Medicine Volume 10 Issue 2 |
| ISSN: | 2077-0383 |
| Popis: | (1) Background: Focal chondral defects of the knee can significantly impair patient quality of life. Although different options are available, they are still not conclusive and have several limitations. The aim of this study was to evaluate the role of autologous cartilage micrografts in the treatment of knee chondropathy. (2) Methods: Eight patients affected by knee chondropathy were evaluated before and after 6 months and 3 years following autologous cartilage micrografts by magnetic resonance imaging (MRI) for cartilage measurement and clinical assessment. (3) Results: All patients recovered daily activities, reporting pain reduction without the need for analgesic therapy Oxford Knee Score (OKS) was 28.4 ± 6 and 40.8 ± 6.2 and visual analogue scale (VAS) was 5.5 ± 1.6 and 1.8 ± 0.7 before and after 6 months following treatment, respectively. Both scores remained stable after 3 years. Lastly, a significant improvement of the cartilage thickness was observed using MRI after 3 years. (4) Conclusions: Autologous cartilage micrografts can promote the formation of new cartilage, and could be a valid approach for the treatment of knee chondropathy. |
| Databáze: | OpenAIRE |
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