Practicable approaches to targeted comparative mapping of rat chromosome regions: linkage mapping of five genes on rat chromosome 13
| Autor: | N. Kato, J.P. Rapp, Gina Hyne, G.M. Lathrop |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
Genetic Linkage Locus (genetics) Biology Rats Inbred WKY Chromosomes Restriction fragment Species Specificity Gene mapping Genetic linkage Histocompatibility Antigens Chromosome regions Renin Genetics Animals Humans Molecular Biology Genetics (clinical) Chromosome 13 Synteny Polymorphism Genetic Gene map Chromosome Mapping Rats Inbred Strains Sequence Analysis DNA Rats Genes Chromosomes Human Pair 1 biology.protein Female Myogenin Calcium Channels Laminin Sodium-Potassium-Exchanging ATPase |
| Zdroj: | Cytogenetic and Genome Research. 81:42-45 |
| ISSN: | 1424-859X 1424-8581 |
| DOI: | 10.1159/000015005 |
| Popis: | We demonstrate feasible approaches to comparative mapping between the region near the renin locus on rat chromosome 13 and human chromosome 1q by assigning five additional genes as anchor loci. Base-substitution polymor- phisms were sought in the 3′- and/or 5′-untranslated regions for subsequent development of PCR-amplified markers, which, in turn, could be used for either restriction fragment analysis or allele-specific PCR. |
| Databáze: | OpenAIRE |
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