Low-boiling Point Perfluorocarbon Nanodroplets as Dual-Phase Dual-Modality MR/US Contrast Agent

Autor:	Christian T. McHugh, Phillip G. Durham, Sebastian Atalla, Michele Kelley, Nicholas J. Bryden, Paul A. Dayton, Rosa T. Branca
Rok vydání:	2022
Předmět:	Fluorocarbons Microbubbles Magnetic Resonance Spectroscopy Contrast Media Physical and Theoretical Chemistry Magnetic Resonance Imaging Atomic and Molecular Physics and Optics
Zdroj:	Chemphyschem : a European journal of chemical physics and physical chemistry. 23(24)
ISSN:	1439-7641
Popis:	Detection of bare gas microbubbles by magnetic resonance (MR) at low concentrations typically used in clinical contrast-ultrasound studies was recently demonstrated using hyperCEST. Despite the enhanced sensitivity achieved with hyperCEST, in vivo translation is challenging as on-resonance saturation of the gas-phase core of microbubbles consequently results in saturation of the gas-phase hyperpolarized
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c62fbd6cd07978a7701e5d7d2123a81 https://pubmed.ncbi.nlm.nih.gov/36037034 Zobrazit plný text záznamu Plný text