Oesophageal acid clearance in patients with systemic sclerosis
| Autor: | Federica Carola, Guido Basilisco, Paolo Pietro Bianchi, M. Vanoli, Roberta Barbera |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Supine position Adolescent Manometry Posture Gastroenterology Esophagus Heartburn Internal medicine Supine Position medicine Esophagitis Humans Esophageal Motility Disorders In patient Aged Peristalsis Scleroderma Systemic Hepatology Esophageal disease Vascular disease business.industry Body position Oesophageal peristalsis Hydrogen-Ion Concentration Middle Aged medicine.disease Deglutition Surgery medicine.anatomical_structure Gastroesophageal Reflux Female Esophagogastric Junction Hydrochloric Acid Deglutition Disorders Intubation business Gravitation |
| Zdroj: | European Journal of Gastroenterology & Hepatology. 8:205-210 |
| ISSN: | 0954-691X |
| DOI: | 10.1097/00042737-199603000-00004 |
| Popis: | OBJECTIVE To test the effect of body position on oesophageal acid clearance time in patients with systemic sclerosis. DESIGN AND METHODS Fifteen consecutive patients with systemic sclerosis and six healthy subjects underwent oesophageal manometry and an acid clearance test in three body positions (supine, recumbent at 30 degrees and seated at 90 degrees) in randomized order. RESULTS In healthy subjects the body position did not affect acid clearance time, whereas in patients the oesophagus cleared mainly by gravity. In patients the acid clearance time was significantly longer in the supine than in the seated position (P < 0.05). Nine patients did not have a detectable peristaltic wave in the distal oesophagus. In the other six oesophageal peristalsis was still detectable but contractions had reduced amplitude and often had double and triple peaks; also in this subgroup the acid clearance time recorded in the supine position was prolonged. CONCLUSIONS In systemic sclerosis gravity plays a major role in oesophageal acid clearance time. The finding of delayed acid clearance in a supine patient may suggest initial oesophageal involvement in the disease. |
| Databáze: | OpenAIRE |
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