Adaptation of the Framingham-Wilson coronary risk equation for the population of Navarra (RICORNA)
| Autor: | J.J. Viñes, Paulino González-Diego, Conchi Moreno-Iribas, Joan Vila, María Jesús Guembe |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male education.field_of_study Coronary event Framingham Risk Score business.industry Cardiovascular risk factors Population Coronary Disease General Medicine Coronary disease Middle Aged Primary disease Risk Assessment Spain Coronary risk Medicine Humans Female education business Mathematics Demography Event (probability theory) Aged |
| Zdroj: | Revista espanola de cardiologia. 62(8) |
| ISSN: | 1579-2242 |
| Popis: | The Framingham equations overestimate the risk of coronary disease in populations with a low disease incidence. It is more appropriate to take the local population's characteristics into account when estimating coronary risk. Accordingly, the Framingham-Wilson equation has been adapted for the population of Navarra, Spain. This article presents 10-year overall coronary risk charts.The Framingham-Wilson equation was adapted using data on the prevalence of cardiovascular risk factors and the coronary event rate in the population of Navarra. The version of the Framingham-Wilson equation used included high-density lipoprotein cholesterol (HDL-C). The probability of an event at 10 years for different combinations of risk factors, with an HDL-C concentration of 35-59 mg/dL, are illustrated.Using the Framingham equation adapted for Navarra (i.e., the RICORNA or Riesgo Coronario Navarra), the proportion with an estimated probability of a coronary event in the next 10 years greater than 9% is approximately half that in the original Framingham population, and the proportion with a high or very high probability (i.e., 20%) is one-third. An HDL-C level35 mg/dL increases the risk by 50% and a levelor =60 mg/dL reduces it by 50%, approximately. The average HDL-C level observed in the population was 63.9 mg/dL overall, and 70.1 mg/dL in women.The RICORNA equation can provide a more precise estimate of overall coronary risk and could be useful in primary disease prevention in Navarra. The high HDL-C concentration observed in Navarra might contribute to the associated low coronary morbidity and mortality. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|