Misoprostol Prior to Diagnostic Office Hysteroscopy in the Subgroup of Patients with No Risk Factors for Cervical Stenosis: A Randomized Double Blind Placebo-Controlled Trial
Autor: | Hesham S. Elshaer, Bahaa Eldin M. Hammad, Ahmed T. Hashem, Ahmed H Attia, Mohamed A. Youssef, Khaled A. Elsetohy, Mona M. Shaban, Usama M. Fouda |
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Rok vydání: | 2017 |
Předmět: |
Adult
medicine.medical_specialty Visual analogue scale Placebo-controlled study Hysteroscopy Pain Procedural Placebo Preoperative care 03 medical and health sciences 0302 clinical medicine Double-Blind Method Pregnancy Risk Factors Oxytocics Preoperative Care Ambulatory Care Humans Medicine Misoprostol Pain Measurement 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics and Gynecology Middle Aged medicine.disease Surgery Administration Intravaginal Stenosis medicine.anatomical_structure Reproductive Medicine 030220 oncology & carcinogenesis Female Uterine cavity business medicine.drug |
Zdroj: | Gynecologic and Obstetric Investigation. 83:455-460 |
ISSN: | 1423-002X 0378-7346 |
DOI: | 10.1159/000480234 |
Popis: | Aims: To assess the effectiveness of vaginal misoprostol in minimizing the pain perceived by patients with no risk factors for cervical stenosis (i.e., parous women of reproductive age who have no history of cesarean section or cervical surgery) during diagnostic office hysteroscopy. Methods: A total of 100 patients with no risk factors for cervical stenosis were randomized to the misoprostol group (n = 50) or the placebo group (n = 50). In the misoprostol group, 2 misoprostol tablets (400 µg) were administered vaginally 12 h before office hysteroscopy. In the placebo group, 2 placebo tablets were administered. The patients rated the intensity of pain perceived during the procedure and at 30 min after the procedure with the use of a 100 mm visual analog scale (VAS). The hysteroscopists also scored the difficulty of hysteroscope insertion into the uterine cavity with the use of a 100 mm VAS. Results: There were no significant differences between both groups in the VAS pain scores during or at 30 min after the procedure (28.3 ± 13.58 vs. 30.42 ± 15.13 and 11.1 ± 10.23 vs. 13.32 ± 11.12, respectively). The difficulty of hysteroscope insertion into the uterine cavity was comparable between both groups. Conclusion: Misoprostol administration prior to diagnostic office hysteroscopy appears to have no beneficial role in the subgroup of patients with no risk factors for cervical stenosis. |
Databáze: | OpenAIRE |
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