Pulmonary vascular disease associated with pulmonary hypertension in 445 patients: diagnosis from lung biopsy and autopsy
| Autor: | Shigeo Yamaki |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Heart Defects
Congenital Heart Septal Defects Ventricular Male Pulmonary and Respiratory Medicine medicine.medical_specialty Adolescent Heart Diseases Heart disease Biopsy Hypertension Pulmonary Chronic thromboembolic pulmonary hypertension Lung biopsy Autopsy Pulmonary Artery Pulmonary hypertension Japan Surgical oncology Cause of Death medicine Humans Prospective Studies cardiovascular diseases Child Lung Congenital heart disease Vascular disease business.industry General Medicine Pulmonary vascular disease medicine.disease Cardiac surgery Pulmonary Veins Cardiothoracic surgery Child Preschool Original Article Female Surgery Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | General Thoracic and Cardiovascular Surgery |
| ISSN: | 1863-6713 1863-6705 |
| Popis: | Purpose Diagnosis from lung biopsy or autopsy was performed in 445 patients with congenital (385) or acquired (60) heart disease from all over Japan. The purpose of this study is the presentation of these prospective data collections. Methods Of the patients with congenital heart disease, 354 were biopsied to determine whether surgery was indicated. Decisions regarding surgery were based on the index of pulmonary vascular disease in simple cardiac anomalies or atrioventricular septal defects (AVSD). In total anomalous pulmonary venous connection (TAPVC), operative indication was determined by the degree of hypoplasia of small pulmonary arteries. Operability of Fontan procedure was based on the degree of residual medial hypertrophy after pulmonary artery banding. Results In patients with simple cardiac anomalies, radical surgery was indicated in 166. Radical surgery was indicated in 50 patients with AVSD. In 26 patients with TAPVC, radical surgery was not indicated in 10. In 68 Fontan candidates, surgery was not indicated in 49. Among 7 patients with tetralogy of Fallot, 1 was not a surgical candidate. Of the 60 acquired heart disease patients, 16 had idiopathic pulmonary arterial hypertension and 36 had chronic thromboembolic pulmonary hypertension. In 6 patients, lung biopsy revealed pulmonary veno-occlusive disease; 2 patients had combined valvular disease. Conclusion The cardiac surgeon, pediatric cardiologist, and cardiologist who requested diagnosis from lung biopsy or autopsy were gratified with the results. |
| Databáze: | OpenAIRE |
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