Extramedullary nasal plasmacytoma arising after polyp excision and the role of the inflammation in tumor development: A case report
| Autor: | Alfredo Di Giovanni, M. C. Cristi, Arianna Di Stadio, Angelo Sidoni, Giampietro Ricci, Massimo Maranzano, Stefano De Crescenzo, Valeria Gambacorta |
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| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty extramedullary nasal plasmacytoma nasal obstruction Inflammation medicine.disease_cause surgery 03 medical and health sciences 0302 clinical medicine otorhinolaryngologic diseases Nasal Cancer Medicine medicine.diagnostic_test Oncogene business.industry Cancer Magnetic resonance imaging Articles medicine.disease Endoscopy tumorigenesis Oncology inflammation 030220 oncology & carcinogenesis polyp Plasmacytoma 030211 gastroenterology & hepatology medicine.symptom business Carcinogenesis |
| Zdroj: | Molecular and Clinical Oncology |
| ISSN: | 2049-9469 2049-9450 |
| Popis: | A correlation between inflammation and cancer has been identified in the case of nasal cancer, however a specific connection between nasal inflammation and extramedullary nasal plasmacytoma (ENP), to the best of our knowledge, has not yet been determined. The present case report describes a patient affected by ENP, in who the tumor arose in the same area, from which a nasal polyp was previously surgically removed, five months after the polyp excision. The patient underwent surgical endoscopic tumor asportation without being treated with radio-chemotherapy. ENP was totally removed via surgery and no signs of recurrence were identified by endoscopy or magnetic resonance imaging during the last check-up 1 year after tumor asportation. It was hypothesized that in this elderly patient, who was exposed to viral infections and pollution for several years, ENP may be correlated to the inflammatory process that occurred after surgery, and this likely contributed to a neoplastic mutation in B-cells. |
| Databáze: | OpenAIRE |
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