Prevalence and Longevity of SARS-CoV-2 Antibodies Among Health Care Workers
| Autor: | Junko Hara, Matthew Zahn, Elmira Burke, Randy German, Deborah Fridman, Philip A. Robinson, Jason R. Bock, Clayton Chau, Michael Brant-Zawadzki, Marcus Breit |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty IgG Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) education prevalence Disease medicine.disease_cause Immunoglobulin G first responders health care workers Major Articles 03 medical and health sciences 0302 clinical medicine Blood serum longevity Internal medicine antibody Health care Medicine 030212 general & internal medicine Coronavirus biology business.industry SARS-CoV-2 virus diseases COVID-19 immunity 030104 developmental biology Infectious Diseases AcademicSubjects/MED00290 Oncology Risk stratification biology.protein Antibody business |
| Zdroj: | Open Forum Infectious Diseases |
| ISSN: | 2328-8957 |
| Popis: | Background Understanding severe acute respiratory syndrome coronavirus 2 antibody prevalence in a spectrum of health care workers (HCWs) may provide benchmarks of susceptibility, help us understand risk stratification, and support enactment of better health policies and procedures. Methods Blood serum was sampled at enrollment and 8-week follow-up from HCWs (n = 3458) and from community first responders (n = 226) for immunoglobulin G (IgG) analyses. Demographics, job duties, location, and coronavirus disease 2019–related information were collected. Results The observed IgG antibody prevalence was 0.93% and 2.58% at enrollment (May/June) and 8-week follow-up (July/August), respectively, for HCWs, and 5.31% and 4.35% for first responders. For HCWs, significant differences (P Conclusions We found considerably lower antibody prevalence among HCWs compared with other published studies. While rigorous safety process measures instituted in our workplace and heightened awareness at and outside of the workplace among our HCWs may have contributed to our findings, the significant discrepancy from our community prevalence warrants further studies on other contributing factors. |
| Databáze: | OpenAIRE |
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