Effect of Diethylstilbestrol, Ascorbic Acid and Vitamin E on Serum Lipid Patterns
| Autor: | C. F. Klopfenstein, W. E. Klopfenstein, R. E. Clegg |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Male
medicine.medical_treatment Cholestyramine Resin Phospholipid Oleic Acids Ascorbic Acid chemistry.chemical_compound medicine Animals Vitamin E Food science Diethylstilbestrol Phospholipids Triglycerides Cholestyramine Vitamin C Triglyceride Cholesterol General Medicine Ascorbic acid Lipids Oleic acid Linoleic Acids chemistry Female lipids (amino acids peptides and proteins) Animal Science and Zoology Chickens Stearic Acids medicine.drug |
| Zdroj: | Poultry Science. 55:1104-1111 |
| ISSN: | 0032-5791 |
| DOI: | 10.3382/ps.0551104 |
| Popis: | The effects of relatively high concentrations of vitamin C, vitamin E and diethylstilbestrol, and various combinations of cholestyramine and diethylstilbestrol on the lipid composition of chicken serum were studied. After DES injection (at concentrations as low as 1 mg. /day for 7 days), levels of triglycerides, phospholipids and cholesterol were much higher, the effect being much more pronounced in the hens. Cholestyramine caused a fourfold decrease in cholesterol in females, a 25% reduction in males. DES consistently caused a redistribution of the esterified fatty acids, increasing the percentage of oleic and reducing percentages of stearic and linoleic acids. Preparative TLC analysis of all constituents showed other variations in fatty acid composition, but there was no other common pattern of change. Vitamin E in the diet caused a significant rise in triglycerides and phospholipids in DES treated birds. When vitamins E and C were fed, triglyceride and phospholipid values decreased. Cholesterol concentration did not vary significantly. With birds receiving both vitamins, diethylstilbestrol seemed to have less effect in. causing the shift to increased percentage of oleic acid in the total esterified fatty acids. |
| Databáze: | OpenAIRE |
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