Consumption of Pulse-Based Meals Improves Lipoprotein Ratios Among Sedentary Office Workers: A Randomized Clinical Trial

Autor: Gord A. Zello, Philip D. Chilibeck, Leandy Bertrand, Shannon Hood-Niefer
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Curr Dev Nutr
Popis: OBJECTIVES: To determine whether improvements in cardiometabolic health occur when providing pulse-based meals to sedentary office workers. METHODS: Using a randomized, single-blind, crossover design participants (n = 26) were assigned to either: A pulse-based diet to replace their regular workplace meals OR their regular diet for 2 months, followed by a one-month washout and then crossed-over to the other diet for 2 months. Blood glucose and insulin response (measured as incremental area under the curve (I-AUC)) to an oral glucose tolerance test, and lipids (i.e., total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), TC: HDL-C, LDL-C: HDL-C) were measured before and after each of the two diet phases. RESULTS: Differences between the pulse-diet phase and the control phase were glucose I-AUC (−20.4 mmol/L), insulin I-AUC (1348 µIU/mL), TC (−0.1 mmol/L), LDL-C (−0.24 mmol/L), HDL-C (0.14 mmol/L), TG (0.07 mmol/L). No statistically significant differences were apparent for any of these changes between diet phases; however, the pulse-based diet significantly decreased TC/HDL-C (−0.22, P = 0.01), and LDL-C/HDL-C (−0.19, P = 0.03) compared to the regular diet. CONCLUSIONS: The lipoprotein ratios are better predictors of cardiovascular risk than the isolated parameters. Ready-to-eat packaged pulse-based meals can easily be incorporated as part of a healthy lifestyle to lower risk of cardiovascular diseases. FUNDING SOURCES: Funded by Weston Foundation, Saskatchewan Pulse Growers, and Saskatchewan Agriculture Development Fund.
Databáze: OpenAIRE