A cyclophilin gene-like sequence maps to human X-chromosome
| Autor: | A. N. K. Jacob, Geeta Kandpal, Rajendra P. Kandpal |
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| Rok vydání: | 1996 |
| Předmět: |
DNA
Complementary X Chromosome Molecular Sequence Data Locus (genetics) Biology Cell Line Cyclophilin A Exon Complementary DNA Genetics Humans Cloning Molecular Chromosomes Artificial Yeast Gene X chromosome Cyclophilin Amino Acid Isomerases Base Sequence Chromosome Mapping Exons Sequence Analysis DNA Cell Biology General Medicine Peptidylprolyl Isomerase Molecular biology Cell culture Chromosome Deletion Carrier Proteins |
| Zdroj: | Somatic Cell and Molecular Genetics. 22:67-73 |
| ISSN: | 1572-9931 0740-7750 |
| DOI: | 10.1007/bf02374377 |
| Popis: | We isolated cDNA fragments encoded in an X-chromosome specific YAC from the locus DXS995 by using direct cDNA selection method. Several of the selected cDNA fragments were identical to various exons of cyclophilin A gene. Hybridization of the selected cyclophilin cDNA fragments to the target YAC, presence of these sequences in an X-chromosome specific phage library and absence of a cross hybridizing fragment in a cell line (XL-45) that contains deletions of the interval Xq21, demonstrates that a cyclophilin like sequence is present in the human X-chromosome. |
| Databáze: | OpenAIRE |
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