A Systematic Review of Dietary Supplements and Alternative Therapies for Weight Loss
| Autor: | Domenica Rubino, Clifford A. Reilly, Katherine Kopatsis, Srividya Kidambi, Katherine H. Saunders, John A. Batsis, John W. Apolzan, Heather B. Blunt, Ryan Shean, Shivani Gundumraj, Pamela J. Bagley, Shalini Gundumraj, Vidita Divan, Abishek Stanley, Sonia Gill, Beverly G. Tchang, Ava Port, Elizabeth Prout Parks, Luai Tabaza, Angela Golden, Scott Kahan, Steven B. Heymsfield |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Complementary Therapies medicine.medical_specialty Web of science Adolescent Endocrinology Diabetes and Metabolism MEDLINE Medicine (miscellaneous) 030209 endocrinology & metabolism CINAHL Cochrane Library Article law.invention 03 medical and health sciences 0302 clinical medicine Endocrinology Randomized controlled trial Weight loss law Weight Loss medicine Humans 030212 general & internal medicine Obesity Intensive care medicine Nutrition and Dietetics business.industry medicine.disease Dietary Supplements medicine.symptom business Weight gain |
| Zdroj: | Obesity (Silver Spring) |
| ISSN: | 1930-739X |
| Popis: | Objective Dietary supplements and alternative therapies are commercialized as a panacea for obesity/weight gain as a result of the minimal regulatory requirements in demonstrating efficacy. These products may indirectly undermine the value of guideline-driven obesity treatments. Included in this study is a systematic review of the literature of purported dietary supplements and alternative therapies for weight loss. Methods A systematic review was conducted to evaluate the efficacy of dietary supplements and alternative therapies for weight loss in participants aged ≥18 years. Searches of Medline (PubMed), Cochrane Library, Web of Science, CINAHL, and Embase (Ovid) were conducted. Risk of bias and results were summarized qualitatively. Results Of the 20,504 citations retrieved in the database search, 1,743 full-text articles were reviewed, 315 of which were randomized controlled trials evaluating the efficacy of 14 purported dietary supplements, therapies, or a combination thereof. Risk of bias and sufficiency of data varied widely. Few studies (n = 52 [16.5%]) were classified as low risk and sufficient to support efficacy. Of these, only 16 (31%) noted significant pre/post intergroup differences in weight (range: 0.3-4.93 kg). Conclusions Dietary supplements and alternative therapies for weight loss have a limited high-quality evidence base of efficacy. Practitioners and patients should be aware of the scientific evidence of claims before recommending use. |
| Databáze: | OpenAIRE |
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