Rifampin-resistant replication of pBR322 derivatives in Escherichia coli cells induced for the SOS response
| Autor: | T R Magee, Tokio Kogoma |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
DNA Replication
DNA Bacterial viruses DNA polymerase II Origin of replication Microbiology DNA polymerase delta Replication factor C Control of chromosome duplication Sequence Homology Nucleic Acid polycyclic compounds Escherichia coli SOS Response Genetics Molecular Biology biology DNA replication Drug Resistance Microbial Chromosomes Bacterial biochemical phenomena metabolism and nutrition DNA Polymerase I Prokaryotic DNA replication biology.protein bacteria Replicon Rifampin DNA polymerase I Research Article Plasmids |
| Zdroj: | Journal of Bacteriology. 173:4736-4741 |
| ISSN: | 1098-5530 0021-9193 |
| DOI: | 10.1128/jb.173.15.4736-4741.1991 |
| Popis: | Replication of plasmid pBR322 in Escherichia coli cells normally requires RNA synthesis and thus is sensitive to rifampin, an inhibitor of RNA polymerase. In cells induced for the SOS response, however, derivatives of pBR322 were found to replicate in the presence of rifampin. This rifampin-resistant replication of pBR322 requires the insertion of certain sequences of DNA. The replication depends on recF+ and DNA polymerase I. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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