Increased liver elasticity in patients with biliary obstruction

Autor: Kenji Hirano, Haruhiko Yoshida, Minoru Tada, Yoko Yashima, Naoki Sasahira, Yousuke Nakai, Ryosuke Tateishi, Takao Kawabe, Masao Omata, Hiroyuki Isayama, Ryota Masuzaki, Takeshi Tsujino
Rok vydání: 2010
Předmět:
Zdroj: Journal of Gastroenterology. 46:86-91
ISSN: 1435-5922
0944-1174
DOI: 10.1007/s00535-010-0290-9
Popis: Transient elastography (with the FibroScan® apparatus) is a recently developed method for evaluating the severity of liver fibrosis by measuring liver elasticity. Liver elasticity may differ from the normal level in patients with obstructive jaundice because the retained bile may expand the liver. Because little is known about liver elasticity in patients with obstructive jaundice, we evaluated this feature in these patients. Between April 2007 and April 2008, 178 patients with biliary or pancreatic disease underwent transient elastography at the University of Tokyo Hospital. We excluded 77 patients because of concomitant cirrhotic liver disease, liver tumors, or a history of abdominal surgery. The remaining 101 patients were included in the study and were divided into obstructive jaundice (OJ; n = 43) and nonobstructive jaundice (NJ; n = 58) groups. The basic patient characteristics did not differ significantly between the two groups, except for the causative diseases. The mean liver elasticity was significantly higher in the OJ group than in the NJ group (12.0 vs. 6.2 kPa, p
Databáze: OpenAIRE
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