Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study
| Autor: | Luong Huu Dang, Chin Hui Su, Lung Che Chen, Yen Chun Chen, Shih Han Hung, Deng Yu Han, Chi Ching Chang, Chung Huei Hsu, Yi Fang Ding |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Disease Gastroenterology Sialadenitis 03 medical and health sciences 0302 clinical medicine Salivary scintigraphy Refractory Internal medicine medicine Chronic sialoadenitis Outpatient clinic Humans Salivary Ducts In patient Post-RAI sialoadenitis Radionuclide Imaging lcsh:R5-920 Office based Salivary gland business.industry General Medicine medicine.anatomical_structure Sjogren's Syndrome 030220 oncology & carcinogenesis Chronic Disease Postradiotherapy sialoadenitis Salivary ductal irrigation 030211 gastroenterology & hepatology lcsh:Medicine (General) business |
| Zdroj: | Journal of the Formosan Medical Association, Vol 120, Iss 1, Pp 318-326 (2021) |
| ISSN: | 0929-6646 |
| Popis: | Background/Purpose To evaluate the therapeutic responsiveness of office-based salivary gland ductal irrigation in patients with chronic sialoadenitis. Methods Between August 2017 and April 2019, 55 patients comprising the following three disease groups were enrolled: Sjogren’s syndrome: 39 patients; postradiotherapy sialoadenitis: ten patients; and post-RAI sialoadenitis: six patients. Quantitative salivary scintigraphy was recorded, and a formulated questionnaire including the Summated Xerostomia Inventory was utilized to assess acute/chronic symptoms. All patients received at least three serial salivary gland ductal irrigations with a one-month interval in our outpatient department. Results The general response rates for each disease groups are as follows: Sjogren’s syndrome: 61.5% (24/39); postradiotherapy: 60% (6/10); and post-RAI: 83.3% (5/6). Among the patients with Sjogren’s syndrome, the parotid scintigraphic Tmin showed a significant positive correlation with the responsiveness of salivary irrigation (P = 0.046), whereas the treatment tended to be irresponsive in patients who previously took medicine for their related discomfort (P = 0.009). In the postradiotherapy and post-RAI groups, no significant factors were found to be associated with the responsiveness of irrigation. Conclusion Simple salivary ductal irrigation without complex equipment can be performed as an outpatient procedure to alleviate glandular swelling or xerostomia in patients with Sjogren's syndrome, postradiotherapy sialoadenitis or post-RAI sialoadenitis, and it can be considered an alternative management approach for patients refractory to conventional strategies. |
| Databáze: | OpenAIRE |
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