Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time
| Autor: | Ufuk Sayar, Ilker Mataraci, Muhammet Onur Hanedan, Ali Arslan, Aşkın Kiliç, Mehmet Ali Yürük |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Erythrocyte transfusion Silver RD1-811 Activated clotting time 030204 cardiovascular system & hematology law.invention 03 medical and health sciences 0302 clinical medicine law medicine Cardiopulmonary bypass Postoperative results Humans Diseases of the circulatory (Cardiovascular) system In patient Hospital Mortality Postoperative Period Cardiac Surgical Procedures Cardiopulmonary Bypass medicine.diagnostic_test business.industry Heparin General Medicine Length of Stay Intensive care unit Cardiac surgery Intensive Care Units Anesthesia RC666-701 Drainage Original Article Surgery Cardiology and Cardiovascular Medicine business Erythrocyte Transfusion medicine.drug |
| Zdroj: | Brazilian Journal of Cardiovascular Surgery, Vol 35, Iss 6, Pp 913-917 (2020) Brazilian Journal of Cardiovascular Surgery, Issue: ahead, Published: 19 JUN 2020 Brazilian Journal of Cardiovascular Surgery, Volume: 35, Issue: 6, Pages: 913-917, Published: 19 JUN 2020 Brazilian Journal of Cardiovascular Surgery v.35 n.6 2020 Brazilian Journal of Cardiovascular Surgery Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) instacron:SBCCV |
| ISSN: | 1678-9741 |
| Popis: | Objective: To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods: A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those receiving heparin-coated circuits (Bioline®, Maquet Cardiopulmonary AG., Hirrlingen, Germany) and those receiving non-coated circuits (Maquet Cardiopulmonary AG., Hirrlingen, Germany). Results: Activated clotting times (ACT) during cardiopulmonary bypass (CPB) were significantly shorter in the heparin-albumin-coated group than in the non-coated group (355.64±34.12 vs. 560.38±90.20, respectively, P=0.001). In-hospital mortality and postoperative stroke rates and lengths of intensive care unit stay were similar between the groups; in contrast, in the heparin-albumin-coated group, patients had significantly better outcomes for hospital stay, drainage, and need for erythrocyte transfusion. Conclusion: Heparin-coated circuits and reduced level of systemic heparinization with 300 seconds of target ACT level in cardiac surgery under CPB are safe and result in a very satisfactory clinical course. |
| Databáze: | OpenAIRE |
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