Challenges to the development of the next generation of self-reporting cardiovascular implantable medical devices
Autor: | Daniel Hoare, John Mercer, Talha Kirimi, Antonia Molley, Kirsten Beaumont, Srinjoy Mitra, Steven L. Neale, Hadi Heidari, Ali Alyami, Nosrat Mirzai |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Biomedical Engineering Disease Cardiovascular Percutaneous Coronary Intervention Restenosis smart medicine Humans Coronary Artery Bypass Precision Medicine Intensive care medicine business.industry Percutaneous coronary intervention Stent Heart Blood flow medicine.disease Precision medicine surgical procedures operative medicine.anatomical_structure implantable medical devices Cardiovascular Diseases graft Conventional PCI impedance Stents stent business Biosensor Artery |
Zdroj: | Molloy, A, Beaumont, K, Kirimi, T, Alyami, A, Hoare, D, Mirzai, N, Heidari, H, Mitra, S, Neale, S L & Mercer, J 2021, ' Challenges to the development of the next generation of self-reporting cardiovascular implantable medical devices. ', IEEE REVIEWS IN BIOMEDICAL ENGINEERING . https://doi.org/10.1109/RBME.2021.3110084 |
ISSN: | 1937-3333 |
Popis: | Cardiovascular disease (CVD) is a group of heart and vasculature conditions which are the leading form of mortality worldwide. Blood vessels can become narrowed, restricting blood flow, and drive the majority of hearts attacks and strokes. Reactive surgical interventions are frequently required; including percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). Despite successful opening of vessels and restoration of blood flow, often in-stent restenosis (ISR) and graft failure can still occur, resulting in subsequent patient morbidity and mortality. A new generation of cardiovascular implants that have sensors and real-time monitoring capabilities are being developed to combat ISR and graft failure. Self-reporting stent/graft technology could enable precision medicine-based and predictive healthcare by detecting the earliest features of disease, even before symptoms occur. Bringing an implantable medical device with wireless electronic sensing capabilities to market is complex and often obstructive undertaking. This critical review analyses the obstacles that need to be overcome for self-reporting stents/grafts to be developed and provide a precision-medicine based healthcare for cardiovascular patients. Here we assess the latest research and technological advancement in the field, the current devices; including smart cardiovascular implantable biosensors and associated wireless data and power transfer solutions. We include an evaluation of device that have reach clinical trials and the market potential for their end-user implementation. |
Databáze: | OpenAIRE |
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