Collision sellar lesions: experience with eight cases and review of the literature
| Autor: | Maria Koutourousiou, Andre J. Grotenhuis, George Kontogeorgos, Pieter Wesseling, Andreas Seretis |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Adenoma ACTH-Secreting Pituitary Adenoma Pathology medicine.medical_specialty endocrine system diseases Endocrinology Diabetes and Metabolism Schwannoma Pituitary neoplasm Article Lesion Endocrinology Translational research [ONCOL 3] Pituitary adenoma medicine Humans Pituitary Neoplasms Sella Turcica Ganglioneuroma Central Nervous System Cysts Aged Retrospective Studies business.industry Histocytochemistry Neoplasms Second Primary Middle Aged medicine.disease Magnetic Resonance Imaging digestive system diseases stomatognathic diseases Sella turcica medicine.anatomical_structure Pituitary Female Nonadenomatous sellar lesions Collision tumors medicine.symptom business Neurilemmoma |
| Zdroj: | Pituitary Pituitary, 13, 8-17 Pituitary, 13, 1, pp. 8-17 |
| ISSN: | 1573-7403 1386-341X |
| Popis: | Contains fulltext : 89259.pdf (Publisher’s version ) (Open Access) The concomitant presence of a pituitary adenoma with a second sellar lesion in patients operated upon for pituitary adenoma is an uncommon entity. Although rare, quite a great variety of lesions have been indentified coexisting with pituitary adenomas. In fact, most combinations have been described before, but an overview with information on the frequency of combined pathologies in a large series has not been published. We present a series of eight collision sellar lesions indentified among 548 transsphenoidally resected pituitary adenomas in two Neurosurgical Departments. The histological studies confirmed a case of sarcoidosis within a non-functioning pituitary adenoma, a case of intrasellar schwannoma coexisting with growth hormone (GH) secreting adenoma, two Rathke's cleft cysts combined with pituitary adenomas, three gangliocytomas associated with GH-secreting adenomas, and a case of a double pituitary adenoma. The pertinent literature is discussed with emphasis on pathogenetic theories of dual sellar lesions. Although there is no direct evidence to confirm the pathogenetic relationship of collision sellar lesions, the number of cases presented in literature makes the theory of an incidental occurrence rather doubtful. Suggested hypotheses about a common embryonic origin or a potential interaction between pituitary adenomas and the immune system are presented. |
| Databáze: | OpenAIRE |
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