Coronavirus Occurrence and Transmission Over 8 Years in the HIVE Cohort of Households in Michigan

Autor: Ryan E. Malosh, Peter M. DeJonge, Arnold S. Monto, Skylar B Capriola, Latifa Bazzi, Emily T. Martin, Amy P Callear, Joshua G. Petrie
Rok vydání: 2020
Předmět:
Zdroj: The Journal of Infectious Diseases
ISSN: 1537-6613
Popis: Background As part of the Household Influenza Vaccine Evaluation (HIVE) study, acute respiratory infections (ARI) have been identified in children and adults from 2010 to 2018. Methods Annually, 890 to 1441 individuals were followed and contacted weekly to report ARIs. Specimens collected during illness were tested for human coronaviruses (HCoV) types OC43, 229E, HKU1, and NL63. Results In total, 993 HCoV infections were identified during the 8 years, with OC43 most commonly seen and 229E the least. HCoVs were detected in a limited time period, between December and April/May and peaked in January/February. Highest infection frequency was in children Conclusions Coronaviruses are sharply seasonal. They appear, based on serial interval and secondary infection risk, to have similar transmission potential to influenza A(H3N2) in the same population.
Databáze: OpenAIRE