Intracellular determinants of picornavirus replication
| Autor: | Andrea V. Gamarnik, Raul Andino, Nina Boddeker, Deborah Silvera |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Microbiology (medical)
Picornavirus viruses Genome Viral Picornaviridae medicine.disease_cause Virus Replication Microbiology Virology medicine Animals Humans Receptor Tropism Host factor biology Poliovirus virus diseases Translation (biology) biology.organism_classification Infectious Diseases Protein Biosynthesis Tissue tropism RNA Viral Receptors Virus Intracellular |
| Zdroj: | Trends in microbiology. 7(2) |
| ISSN: | 0966-842X |
| Popis: | Viruses replicate in a restricted number of hosts and tissues. In addition to viral receptors, several intracellular factors can be involved in determining tissue tropism. Many proteins have recently been implicated in picornavirus translation and RNA replication. Although the functional role of these proteins has not been established in vivo, it is possible that they determine cell-type tropism and the pathogenic outcome of the infection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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