A hemocyte-expressed fibrinogen-related protein gene ( Lv Frep) from the shrimp Litopenaeus vannamei : Expression analysis after microbial infection and during larval development
| Autor: | Cairé Barreto, Rafael Diego Rosa, Luciane Maria Perazzolo, Amanda da Silva Silveira, Jaqueline da Rosa Coelho, Graziela Vieira |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Hemocytes animal structures White spot syndrome Litopenaeus Aquatic Science Microbiology 03 medical and health sciences White spot syndrome virus 1 Penaeidae Sequence Analysis Protein Gene expression Animals Environmental Chemistry Gene Phylogeny Ovum Vibrio biology Vibrio harveyi Fibrinogen 04 agricultural and veterinary sciences General Medicine biology.organism_classification Crustacean Shrimp Fishery 030104 developmental biology Gene Expression Regulation 040102 fisheries 0401 agriculture forestry and fisheries |
| Zdroj: | Fish & Shellfish Immunology. 56:123-126 |
| ISSN: | 1050-4648 |
| DOI: | 10.1016/j.fsi.2016.06.046 |
| Popis: | Fibrinogen-related proteins (FREPs) comprise a large family of microbial recognition proteins involved in many biological functions in both vertebrate and invertebrate animals. By taking advantage of publicly accessible databases, we have identified a FREP-like homolog in the most cultivated penaeid shrimp, Litopenaeus vannamei (LvFrep). The obtained sequence showed a conserved fibrinogen-related domain (FReD) and displayed significant similarities to FREP-like proteins from other invertebrates and to ficolins from crustaceans. The expression of LvFrep appeared to be limited to circulating hemocytes. Interestingly, LvFrep gene expression was induced in shrimp hemocytes only in response to a Vibrio infection but not to the White spot syndrome virus (WSSV). Moreover, LvFrep transcript levels were detected early in fertilized eggs, suggesting the participation of this immune-related gene in the antimicrobial defenses during shrimp development. |
| Databáze: | OpenAIRE |
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