Observational study of cone beam computed tomography based interfractional urinary bladder filling variation during image guided radiation therapy in pelvic malignancies
Autor: | Sudarsan De, Sweety Gupta, Sandeep Agarwal, Manjari Shah, Bala Subramanian, Rashi Agarwal, Shiv S Mishra |
---|---|
Rok vydání: | 2021 |
Předmět: |
Male
Cone beam computed tomography medicine.medical_treatment Urinary Bladder Planning target volume Uterine Cervical Neoplasms urologic and male genital diseases Standard deviation Motion Medicine Humans Radiology Nuclear Medicine and imaging Transverse diameter Reduction (orthopedic surgery) Image-guided radiation therapy Pelvic Neoplasms Urinary bladder business.industry Prostatic Neoplasms Radiotherapy Dosage General Medicine Cone-Beam Computed Tomography Endometrial Neoplasms medicine.anatomical_structure Oncology Bladder volume Female business Nuclear medicine Colorectal Neoplasms Radiotherapy Image-Guided |
Zdroj: | Journal of cancer research and therapeutics. 17(1) |
ISSN: | 1998-4138 |
Popis: | Background Organ motion is an important factor that limits the precision of radiation treatment. Bladder filling variation has significant impact on the position of target volumes in pelvic malignancies. Aims and objective This study was an effort to maintain a consistent urinary bladder volume after following a bladder protocol, which was then analyzed by in-room cone-beam computed tomography (CBCT) imaging. Material and methods A total number of 26 patients/300 scans, i.e. 26 planning scan and 274 CBCT were analyzed. The bladder volumes and bladder wall dimension were analyzed comprehensively, thus adding considerable understanding to the bladder wall motions. Result The mean bladder volume for all 26 patients was 183.07 cc with standard deviation of 90.43 cc. The mean +/- standard deviation of transverse, anteroposterior and longitudinal diameter was 8.35+/- 1.03, 6.69+/-1.05 and 5.59+/-1.79 cm. Conclusion This study showed considerable reduction of margin could be done on the lateral side, as there is less displacement on transverse diameter and more liberal margins should be considered in anteroposterior dimension and longitudinal dimensions. This study has reached the conclusion that bladder-filling protocol is necessary to maintain the consistent bladder volume, but it is too preliminary to state that it will translate into reduction of margin. |
Databáze: | OpenAIRE |
Externí odkaz: | |
Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |