Cimetidine suspension in patients with Stage 0 gastro-oesophageal reflux disease
| Autor: | J. F. Riemann, W. Höbel |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Placebo Gastroenterology Double-Blind Method Heartburn Suspensions Histamine H2 receptor Gastro Internal medicine medicine Humans Pharmacology (medical) Cimetidine Aged Chemotherapy Hepatology business.industry Reflux Middle Aged Regurgitation (digestion) Gastroesophageal Reflux Female medicine.symptom business medicine.drug |
| Zdroj: | Alimentary Pharmacology & Therapeutics. 5:191-197 |
| ISSN: | 1365-2036 0269-2813 |
| DOI: | 10.1111/j.1365-2036.1991.tb00020.x |
| Popis: | One hundred and twenty-five patients with symptoms of heartburn and acid regurgitation but without endoscopic abnormalities were randomized to receive 200 mg cimetidine suspension four times daily or placebo for two weeks. Daily dairy cards were kept to evaluate the frequency and degree of symptoms. At two weeks cimetidine was significantly more effective than placebo. It is concluded that placebo suspension has a considerable effect on gastro-oesophageal reflux disease symptoms, but cimetidine suspension provides significantly better relief. |
| Databáze: | OpenAIRE |
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