Management of adult testicular germ cell tumours: summary of updated SIGN guideline
| Autor: | G C W, Howard, M, Nairn, Phil, Wilson |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Referral media_common.quotation_subject Fertility Testicular Neoplasms Humans Medicine Neoplasm Metastasis Physical Examination Referral and Consultation Grading (tumors) Neoplasm Staging General Environmental Science media_common Gynecology business.industry General Engineering Five-year survival rate General Medicine Guideline Neoplasms Germ Cell and Embryonal Testicular germ cell Systematic review Practice Guidelines as Topic General Earth and Planetary Sciences Long Term Adverse Effects Neoplasm Recurrence Local business |
| Zdroj: | BMJ. 342:d2005-d2005 |
| ISSN: | 1468-5833 0959-8138 |
| DOI: | 10.1136/bmj.d2005 |
| Popis: | Testicular germ cell tumours are rare. In 2008, 203 new cases were diagnosed in Scotland,1 with a crude incidence of 8.1 cases per 100 000 of the male population.2 It is the 15th most common cancer among all men in Scotland1 and the most common cancer in younger adult men.3 It is one of the few curable solid cancers, even when it has metastasised, and has a crude overall five year survival rate in Scotland of 95.8%.1 Although the cure rate is high, the toxicity of treatment is substantial, resulting in treatment related deaths and long term adverse effects. Potential effects on employment and fertility are of particular importance in this age group. This article summarises the most recent recommendations from the Scottish Intercollegiate Guidelines Network (SIGN) on the management of adult testicular germ cell tumours,4 updating 1998 SIGN guidelines on this condition. SIGN recommendations are based on systematic reviews of best available evidence. The strength of the evidence is graded as A, B, C, or D (figure⇓), but the grading does not reflect the clinical importance of the recommendations. Recommended best practice (“good practice points”), based on the clinical experience of the Guideline Development Group, is also indicated (as GPP). Explanation of SIGN grades of recommendations ### Initial assessment and referral in primary care |
| Databáze: | OpenAIRE |
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